cas 2304513-76-4|| where to buy 3-(6-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione

Produktname:3-(6-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione

IUPAC Name:3-(6-bromo-1-oxo-2,3-dihydro-1H-isoindol-2-yl)piperidine-2,6-dione

: CAS：2304513-76-4; Molekulare Formel：C13H11BrN2O3; Reinheit：95%+

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CM621861-25g	in stock	ǙħǸ

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: CAS-Nr.:2304513-76-4; Molekulare Formel:C13H11BrN2O3; Schmelzpunkt:-; SMILES-Code:BrC1=CC2=C(CN(C3CCC(=O)NC3=O)C2=O)C=C1; Dichte:

: Katalognummer:CM621861; Molekulargewicht:323.15; Siedepunkt:; Mdl-Nr.:; Lagerung:

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: MRT-2359; Aberrant MYC pathway activation is found in cancer cells, while MYC-induced protein translation depends on GSPT1. Molecular glues targeting GSPT1 is identified as a potential treatment method in oncology. Monte Rosa’s MRT-2359 is an oral and selective molecular glue degrader of the translation termination factor GSPT1. The targeted GSPT1 degradation results in disrupting MYC-driven protein translation and reducing MYC-oncogenic signaling.
MRT-2359 is in an ongoing phase 1/2 study in MYC-driven solid tumors with a current assessment of 0.75 mg dose level. The final phase 2 dose determination and updated clinical results are anticipated in the second half of 2024. MRT-2359 previously received Fast Track Designation in patients with previously treated, metastatic NSCLC with L-MYC or N-MYC expression, Orphan Drug Designation in small cell lung cancer (SCLC), and Fast Track Designation in previously treated, metastatic SCLC with L-MYC or N-MYC expression.