cas 2306260-74-0|| where to buy 1,7-dioxaspiro[3.5]nonan-3-amine

Produktname:1,7-dioxaspiro[3.5]nonan-3-amine

IUPAC Name:1,7-dioxaspiro[3.5]nonan-3-amine

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: CAS-Nr.:2306260-74-0; Molekulare Formel:C7H13NO2; Schmelzpunkt:-; SMILES-Code:NC1COC12CCOCC2; Dichte:

: Katalognummer:CM1018239; Molekulargewicht:143.19; Siedepunkt:; Mdl-Nr.:; Lagerung:

: Oxetanes; Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.

: Tetrahydropyrans; Tetrahydropyran is an organic compound consisting of a saturated six-membered ring containing five carbon atoms and one oxygen atom. Tetrahydropyrans are common structural motifs in natural products and synthetic therapeutic molecules. In nature, these six-membered oxygen heterocycles are usually assembled by intramolecular reactions, including oxygen Michael addition or ring opening of epoxy alcohols. In fact, polyether natural products have been particularly extensively studied for their fascinating structures and important biological properties; these are often formed through endoselective epoxy open cascades.