Produktname:5-(but-3-ynylamino)-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione
IUPAC Name:5-[(but-3-yn-1-yl)amino]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
- CAS：2357113-11-0
- Molekulare Formel：C17H15N3O4
- Reinheit：95%
- Katalognummer：CM1077322
- Molekulargewicht：325.32
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Produkt-Details
- CAS-Nr.:2357113-11-0
- Molekulare Formel:C17H15N3O4
- Schmelzpunkt:-
- SMILES-Code:O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(NCCC#C)=CC=C12
- Dichte:
- Katalognummer:CM1077322
- Molekulargewicht:325.32
- Siedepunkt:
- Mdl-Nr.:
- Lagerung:
Category Infos
- PROTAC-E3 Ligase Ligands
- Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
- PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.
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