Produktname:dimethyl({[3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl})amine
IUPAC Name:dimethyl({[3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl})amine
- CAS：2369772-15-4
- Molekulare Formel：C16H26BNO2
- Reinheit：95%+
- Katalognummer：CM1077583
- Molekulargewicht：275.2
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Produkt-Details
- CAS-Nr.:2369772-15-4
- Molekulare Formel:C16H26BNO2
- Schmelzpunkt:-
- SMILES-Code:CN(C)CC1=CC=C(B2OC(C)(C)C(C)(C)O2)C(C)=C1
- Dichte:
- Katalognummer:CM1077583
- Molekulargewicht:275.2
- Siedepunkt:
- Mdl-Nr.:
- Lagerung:
Category Infos
- Boronic Acids and Esters
- Boronic acids and boronate esters are commonly used reagents in Suzuki–Miyaura coupling chemistry. Organoboron derivatives are common reagents for C–C bond formation, either through classical palladium-mediated transformations or through other newer coupling methods. Boronic esters and acids are potential intermediates in the manufacture of many active pharmaceutical ingredients (API).
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Column Infos
- ORIC-944
- ORIC-944 is a potent and selective allosteric inhibitor of PRC2 developed by ORIC Pharmaceuticals. Initiated dosing of ORIC-944 in combination with NUBEQA® (darolutamide) and in combination with ERLEADA® (apalutamide) in the ongoing Phase 1b trial for prostate cancer in first half of 2024. Entered into clinical trial collaboration and supply agreements with Bayer and Johnson & Johnson to support the ongoing Phase 1b trial of ORIC-944 in combinations with AR inhibitors for the treatment of prostate cancer.
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