Produktname:(R)-3H-spiro[benzofuran-2,4'-piperidin]-3-amine dihydrochloride
IUPAC Name:(3R)-3H-spiro[1-benzofuran-2,4'-piperidin]-3-amine dihydrochloride
- CAS:2377356-06-2
- Molekulare Formel:C12H18Cl2N2O
- Reinheit:95%+
- Katalognummer:CM454042
- Molekulargewicht:277.19
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Produkt-Details
- CAS-Nr.:2377356-06-2
- Molekulare Formel:C12H18Cl2N2O
- Schmelzpunkt:-
- SMILES-Code:Cl.Cl.N[C@@H]1C2=CC=CC=C2OC11CCNCC1
- Dichte:
- Katalognummer:CM454042
- Molekulargewicht:277.19
- Siedepunkt:
- Mdl-Nr.:
- Lagerung:
Category Infos
- Piperidines
- Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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Column Infos
- GDC-1971
- Protein tyrosine phosphatase SHP2 mediates RAS-driven MAPK signaling and has emerged in recent years as a target of interest in oncology, both for treating with a single agent and in combination with a KRAS inhibitor. GDC-1971 (formerly RLY-1971) is a SHP2 inhibitor currently in clinical trials in combination with KRAS G12C inhibitor divarasib (GDC-6036) for the treatment of solid tumors driven by a KRAS G12C mutation.