Produktname:(R)-3H-spiro[benzofuran-2,4'-piperidin]-3-amine dihydrochloride

IUPAC Name:(3R)-3H-spiro[1-benzofuran-2,4'-piperidin]-3-amine dihydrochloride

CAS:2377356-06-2
Molekulare Formel:C12H18Cl2N2O
Reinheit:95%+
Katalognummer:CM454042
Molekulargewicht:277.19

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Produkt-Details

CAS-Nr.:2377356-06-2
Molekulare Formel:C12H18Cl2N2O
Schmelzpunkt:-
SMILES-Code:Cl.Cl.N[C@@H]1C2=CC=CC=C2OC11CCNCC1
Dichte:
Katalognummer:CM454042
Molekulargewicht:277.19
Siedepunkt:
Mdl-Nr.:
Lagerung:

Category Infos

Piperidines
Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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Column Infos

GDC-1971
Protein tyrosine phosphatase SHP2 mediates RAS-driven MAPK signaling and has emerged in recent years as a target of interest in oncology, both for treating with a single agent and in combination with a KRAS inhibitor. GDC-1971 (formerly RLY-1971) is a SHP2 inhibitor currently in clinical trials in combination with KRAS G12C inhibitor divarasib (GDC-6036) for the treatment of solid tumors driven by a KRAS G12C mutation.

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