Produktname:2-(2,6-dioxo-3-piperidyl)-N-isopropyl-1-oxo-isoindoline-5-carboxamide
IUPAC Name:2-(2,6-dioxopiperidin-3-yl)-1-oxo-N-(propan-2-yl)-2,3-dihydro-1H-isoindole-5-carboxamide
- CAS:2390408-70-3
- Molekulare Formel:C17H19N3O4
- Reinheit:95%
- Katalognummer:CM1076394
- Molekulargewicht:329.36
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Produkt-Details
- CAS-Nr.:2390408-70-3
- Molekulare Formel:C17H19N3O4
- Schmelzpunkt:-
- SMILES-Code:CC(C)NC(=O)C1=CC=C2C(CN(C3CCC(=O)NC3=O)C2=O)=C1
- Dichte:
- Katalognummer:CM1076394
- Molekulargewicht:329.36
- Siedepunkt:
- Mdl-Nr.:
- Lagerung:
Category Infos
- PROTAC-E3 Ligase Ligands
- Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
- PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.