Produktname:2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid
IUPAC Name:2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid
- CAS:23945-44-0
- Molekulare Formel:C5H4N2O4
- Reinheit:97%
- Katalognummer:CM104193
- Molekulargewicht:156.1
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Produkt-Details
- CAS-Nr.:23945-44-0
- Molekulare Formel:C5H4N2O4
- Schmelzpunkt:-
- SMILES-Code:OC(=O)C1=CNC(=O)NC1=O
- Dichte:
- Katalognummer:CM104193
- Molekulargewicht:156.1
- Siedepunkt:
- Mdl-Nr.:MFCD00075737
- Lagerung:
Category Infos
- Pyrimidines
- Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.
Column Infos
- Cerdulatinib
- Cerdulatinib is a small molecule SYK/JAK kinase inhibitor in development for treatment of hematological malignancies. It has lowest nM IC50 values against TYK2, JAK1, JAK2, JAK3, FMS, and SYK. Cerdulatinib is a reversible ATP-competitive dual JAK and Syk inhibitor. The FDA granted orphan drug status to cerdulatinib for the treatment of peripheral T-cell lymphoma (PTCL).