Produktname:2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid

IUPAC Name:2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid

CAS:23945-44-0
Molekulare Formel:C5H4N2O4
Reinheit:97%
Katalognummer:CM104193
Molekulargewicht:156.1

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Produkt-Details

CAS-Nr.:23945-44-0
Molekulare Formel:C5H4N2O4
Schmelzpunkt:-
SMILES-Code:OC(=O)C1=CNC(=O)NC1=O
Dichte:
Katalognummer:CM104193
Molekulargewicht:156.1
Siedepunkt:
Mdl-Nr.:MFCD00075737
Lagerung:

Category Infos

Pyrimidines
Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.

Column Infos

Cerdulatinib
Cerdulatinib is a small molecule SYK/JAK kinase inhibitor in development for treatment of hematological malignancies. It has lowest nM IC50 values against TYK2, JAK1, JAK2, JAK3, FMS, and SYK. Cerdulatinib is a reversible ATP-competitive dual JAK and Syk inhibitor. The FDA granted orphan drug status to cerdulatinib for the treatment of peripheral T-cell lymphoma (PTCL).