Produktname:1-(4-{[1-({imidazo[1,2-a]pyridin-2-yl}methyl)piperidin-4-yl]oxy}but-2-yn-1-yl)-4-methylpiperazine

IUPAC Name:1-(4-{[1-({imidazo[1,2-a]pyridin-2-yl}methyl)piperidin-4-yl]oxy}but-2-yn-1-yl)-4-methylpiperazine

CAS:2415601-79-3
Molekulare Formel:C22H31N5O
Reinheit:95%+
Katalognummer:CM610868
Molekulargewicht:381.52

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Produkt-Details

CAS-Nr.:2415601-79-3
Molekulare Formel:C22H31N5O
Schmelzpunkt:-
SMILES-Code:CN1CCN(CC#CCOC2CCN(CC3=CN4C=CC=CC4=N3)CC2)CC1
Dichte:
Katalognummer:CM610868
Molekulargewicht:381.52
Siedepunkt:
Mdl-Nr.:
Lagerung:

Category Infos

Piperidines
Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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Piperazines
Piperazine is an organic compound consisting of a six-membered ring containing two nitrogen atoms in opposite positions in the ring. The chemical formula of piperazine is C4H10N2, and it is an important pharmaceutical intermediate. Pyrimidines and piperazines are known to be the backbone of many bulk compounds and important core structures for approved drugs; studies have shown that combining a pyridine ring with a piperazine moiety within a single structural framework enhances biological activity.
Imidazopyridines
With four imidazopyridine-containing drugs and one pyrazolopyridine-containing drug on the market, bicyclic pyridines containing ring-junction nitrogen are privileged structures in medicinal chemistry. With two nitrogen atoms with potential to serve as hydrogen bond acceptors, imidazopyridines and pyrazolopyridines may boost binding to target proteins and elevate potency. In addition, these structures have found utility in FBDD, covalent inhibitors, reducing metabolic liabilities, and creating novel chemical space and intellectual properties. With many of the advanced intermediates now commercially available, they will find more and more applications in drug discovery.
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