Produktname:6,7-Dihydro-2H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3(5H)-one

IUPAC Name:3,4-diazatricyclo[9.4.0.0²,⁷]pentadeca-1(15),2,6,11,13-pentaen-5-one

CAS:25823-52-3
Molekulare Formel:C13H12N2O
Reinheit:95%
Katalognummer:CM324062
Molekulargewicht:212.25

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Produkt-Details

CAS-Nr.:25823-52-3
Molekulare Formel:C13H12N2O
Schmelzpunkt:-
SMILES-Code:O=C1C=C(CCCC2=CC=CC=C23)C3=NN1
Dichte:
Katalognummer:CM324062
Molekulargewicht:212.25
Siedepunkt:
Mdl-Nr.:MFCD16871353
Lagerung:

Column Infos

Bemcentinib
Bemcentinib is a potentially first-in-class selective AXL inhibitor in development for STK11 mutated NSCLC and severe respiratory infections. Extensive studies confirm the ability to combine bemcentinib with immune checkpoint inhibitors, chemotherapies and targeted therapies with the goal of improving a patient’s immune response and delaying the development of chemoresistance. Bemcentinib is currently being investigated in combination with immune checkpoint inhibition and chemotherapy in first line NSCLC patients harboring mutations in the STK11 gene, a known prognostic factor of poor response to existing therapies.

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