Produktname:[(2S)-1,1,1-trifluoropropan-2-yl]hydrazine hydrochloride

IUPAC Name:[(2S)-1,1,1-trifluoropropan-2-yl]hydrazine hydrochloride

CAS:2764851-03-6
Molekulare Formel:C3H8ClF3N2
Reinheit:95%+
Katalognummer:CM1046608
Molekulargewicht:164.56

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Produkt-Details

CAS-Nr.:2764851-03-6
Molekulare Formel:C3H8ClF3N2
Schmelzpunkt:-
SMILES-Code:C[C@@H](C(F)(F)F)NN.Cl
Dichte:
Katalognummer:CM1046608
Molekulargewicht:164.56
Siedepunkt:
Mdl-Nr.:
Lagerung:

Category Infos

Fluorinated Compounds
Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.

Column Infos

Pirtobrutinib
Eli Lilly and Company announced that the U.S. FDA approved Jaypirca® (Pirtobrutinib) for the treatment of adult patients with chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL/SLL) who have received at least two prior lines of therapy, including a Bruton's tyrosine kinase (BTK) inhibitor and a BCL-2 inhibitor. Jaypirca (Pirtobrutinib) is a highly selective (300 times more selective for BTK versus 98% of other kinases tested in preclinical studies), non-covalent (reversible) inhibitor of the enzyme BTK.
Chemenu has been working to develop more compounds for drug discovery. Here are the building blocks we can provide.