Produktname:1-(3H-benzotriazol-5-yl)hexahydropyrimidine-2,4-dione

IUPAC Name:1-(1H-1,2,3-benzotriazol-6-yl)-1,3-diazinane-2,4-dione

CAS:2766178-56-5
Molekulare Formel:C10H9N5O2
Reinheit:95%
Katalognummer:CM1077313
Molekulargewicht:231.22

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Produkt-Details

CAS-Nr.:2766178-56-5
Molekulare Formel:C10H9N5O2
Schmelzpunkt:-
SMILES-Code:O=C1CCN(C(=O)N1)C1=CC=C2N=NNC2=C1
Dichte:
Katalognummer:CM1077313
Molekulargewicht:231.22
Siedepunkt:
Mdl-Nr.:
Lagerung:

Category Infos

PROTAC-E3 Ligase Ligands
Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.

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