Produktname:[2-(2,6-dioxo-3-piperidyl)-3-oxo-isoindolin-5-yl]methyl N-[2-fluoro-4-methyl-5-(trifluoromethoxy)phenyl]carbamate

IUPAC Name:[2-(2,6-dioxopiperidin-3-yl)-3-oxo-2,3-dihydro-1H-isoindol-5-yl]methyl N-[2-fluoro-4-methyl-5-(trifluoromethoxy)phenyl]carbamate

CAS:2803881-73-2
Molekulare Formel:C23H19F4N3O6
Reinheit:95%
Katalognummer:CM1076470
Molekulargewicht:509.41

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Produkt-Details

CAS-Nr.:2803881-73-2
Molekulare Formel:C23H19F4N3O6
Schmelzpunkt:-
SMILES-Code:CC1=C(OC(F)(F)F)C=C(NC(=O)OCC2=CC=C3CN(C4CCC(=O)NC4=O)C(=O)C3=C2)C(F)=C1
Dichte:
Katalognummer:CM1076470
Molekulargewicht:509.41
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Mdl-Nr.:
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Category Infos

PROTAC-E3 Ligase Ligands
Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.