cas 28875-17-4|| where to buy N-Boc-L-alanine Methyl Ester

Produktname:N-Boc-L-alanine Methyl Ester

IUPAC Name:methyl (2S)-2-{[(tert-butoxy)carbonyl]amino}propanoate

Packungseinheit	Verfügbarer Vorrat	Preis($)
CM119523-25g	1-2 Weeks	ȷƱ
CM119523-100g	3-4 Weeks	ƻƱſ

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: CAS-Nr.:28875-17-4; Molekulare Formel:C9H17NO4; Schmelzpunkt:-; SMILES-Code:C[C@@H](C(OC)=O)NC(OC(C)(C)C)=O; Dichte:

: Katalognummer:CM119523; Molekulargewicht:203.24; Siedepunkt:; Mdl-Nr.:MFCD00038513; Lagerung:

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: PF-06648671; The Journal of Medicinal Chemistry recently publishes an article titled, “Discovery of Clinical Candidate PF-06648671: A Potent γ-Secretase Modulator for the Treatment of Alzheimer’s Disease”. Amyloid β-peptide (Aβ) accumulation is one of the key hallmarks of Alzheimer’s disease (AD). γ-secretase cleaves the amyloid precursor protein (APP) into pathologically relevant Aβs, and has been widely studied as a potential target for the treatment of AD.
Pfizer‘s PF-06648671 is a Gamma secretase modulator (GSM) targeting APP processing. It is found to have excellent central exposure in human and robust reduction of amyloidogenic forms (Aβ42) in cerebrospinal fluid (CSF).