Produktname:2,4-dichloropyrimidine-5-carbonyl chloride
IUPAC Name:2,4-dichloropyrimidine-5-carbonyl chloride
- CAS:2972-52-3
- Molekulare Formel:C5HCl3N2O
- Reinheit:95%+
- Katalognummer:CM100730
- Molekulargewicht:211.43
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Produkt-Details
- CAS-Nr.:2972-52-3
- Molekulare Formel:C5HCl3N2O
- Schmelzpunkt:-
- SMILES-Code:O=C(Cl)C1=CN=C(Cl)N=C1Cl
- Dichte:1.675g/cm3
- Katalognummer:CM100730
- Molekulargewicht:211.43
- Siedepunkt:304.3°C at 760 mmHg
- Mdl-Nr.:MFCD09742432
- Lagerung:Store at 2-8°C.
Category Infos
- Pyrimidines
- Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.
Column Infos
- Cerdulatinib
- Cerdulatinib is a small molecule SYK/JAK kinase inhibitor in development for treatment of hematological malignancies. It has lowest nM IC50 values against TYK2, JAK1, JAK2, JAK3, FMS, and SYK. Cerdulatinib is a reversible ATP-competitive dual JAK and Syk inhibitor. The FDA granted orphan drug status to cerdulatinib for the treatment of peripheral T-cell lymphoma (PTCL).