Produktname:methyl 3-(methoxymethyl)-1H-pyrazole-4-carboxylate

IUPAC Name:methyl 3-(methoxymethyl)-1H-pyrazole-4-carboxylate

CAS:318496-66-1
Molekulare Formel:C7H10N2O3
Reinheit:95%+
Katalognummer:CM1045731
Molekulargewicht:170.17

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Produkt-Details

CAS-Nr.:318496-66-1
Molekulare Formel:C7H10N2O3
Schmelzpunkt:-
SMILES-Code:COCC1=NNC=C1C(=O)OC
Dichte:
Katalognummer:CM1045731
Molekulargewicht:170.17
Siedepunkt:
Mdl-Nr.:
Lagerung:

Category Infos

Pyrazoles
Pyrazoles are organic compounds of the general formula C3H3N2H. It is a five-membered heterocycle consisting of three carbon atoms and two adjacent nitrogen atoms. As an H-bond-donating heterocycle, pyrazole has been used as a more lipophilic and metabolically more stable bioisomer of phenol. Pyrazoles have attracted more and more attention due to their broad spectrum of action and strong efficacy.
Pyrazone
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Column Infos

Sebetralstat
KalVista Pharmaceuticals recently announces Phase 3 KONFIDENT trial of Sebetralstat meets all primary and key secondary endpoints as first oral on-demand therapy for Hereditary Angioedema (HAE). HAE is a rare and potentially life-threatening genetic disease caused by low levels or dysfunction of the C1 inhibitor, associated with uncontrolled plasma kallikrein (PKa) activity and generation of bradykinin (BK).
Sebetralstat is an investigational novel, oral plasma kallikrein inhibitor with a favorable safety profile. It works by targeting the kallikrein–kinin system (KKS), reducing the activity of plasma kallikrein and blocking uncontrolled bradykinin release in HAE attack. The Phase 3 results also show rapid symptom relief in a broad HAE population.