Produktname:3-bromothioanisole
IUPAC Name:1-bromo-3-(methylsulfanyl)benzene
- CAS：33733-73-2
- Molekulare Formel：C7H7BrS
- Reinheit：95%+
- Katalognummer：CM343628
- Molekulargewicht：203.1
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Produkt-Details
- CAS-Nr.:33733-73-2
- Molekulare Formel:C7H7BrS
- Schmelzpunkt:-
- SMILES-Code:CSC1=CC=CC(Br)=C1
- Dichte:
- Katalognummer:CM343628
- Molekulargewicht:203.1
- Siedepunkt:
- Mdl-Nr.:MFCD00041395
- Lagerung:
Category Infos
- Benzenes
- Benzene is an important organic compound with the chemical formula C6H6, and its molecule consists of a ring of 6 carbon atoms, each with 1 hydrogen atom. Benzene is a sweet, flammable, colorless and transparent liquid with carcinogenic toxicity at room temperature, and has a strong aromatic odor. It is insoluble in water, easily soluble in organic solvents, and can also be used as an organic solvent itself. The ring system of benzene is called benzene ring, and the structure after removing one hydrogen atom from the benzene ring is called phenyl. Benzene is one of the most important basic organic chemical raw materials. Many important chemical intermediates can be derived from benzene through substitution reaction, addition reaction and benzene ring cleavage reaction.
Column Infos
- LTGO-33
- Voltage-gated sodium channels (NaVs) are responsible for action potential initiation and transmission of pain signals. NaV1.8 is specifically expressed in peripheral nociceptors and has been genetically and pharmacologically validated as a human pain target.
LTGO-33 inhibited NaV1.8 in the nM potency range and exhibited over 600-fold selectivity against human NaV1.1-NaV1.7 and NaV1.9. Unlike prior reported NaV1.8 inhibitors that preferentially interacted with an inactivated state via the pore region, LTGO-33 was state-independent with similar potencies against closed and inactivated channels.
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