Produktname:4-CYCLOPROPYL-5-(4-METHYL-1,2,3-THIADIAZOL-5-YL)-4H-1,2,4-TRIAZOLE-3-THIOL

IUPAC Name:4-cyclopropyl-5-(4-methyl-1,2,3-thiadiazol-5-yl)-4H-1,2,4-triazole-3-thiol

CAS:352018-98-5
Molekulare Formel:C8H9N5S2
Reinheit:95%+
Katalognummer:CM382949
Molekulargewicht:239.32

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Produkt-Details

CAS-Nr.:352018-98-5
Molekulare Formel:C8H9N5S2
Schmelzpunkt:-
SMILES-Code:CC1=C(SN=N1)C1=NN=C(S)N1C1CC1
Dichte:
Katalognummer:CM382949
Molekulargewicht:239.32
Siedepunkt:
Mdl-Nr.:
Lagerung:

Category Infos

Triazoles
Triazole refers to a heterocyclic compound with the molecular formula C2H3N3, which has a five-membered ring consisting of two carbon atoms and three nitrogen atoms. Neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease already affect many people around the world, and these numbers are increasing rapidly. Treatment for these disorders is often aimed at relieving symptoms and has no cure. Research on new molecules is underway, and heterocyclic compounds have important pharmacological implications. Triazoles and tetrazoles are emerging as new molecules in this field.
Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.
Thiadiazoles
Thiadiazoles are a subfamily of azoles. Structurally, they are five-membered heterocyclic compounds containing two nitrogen atoms and one sulfur atom, and two double bonds, forming an aromatic ring. Depending on the relative positions of the heteroatoms, there are four possible structures; these forms do not interconvert and are therefore structural isomers rather than tautomers. These compounds themselves are rarely synthesized and have no particular utility, however, compounds that use them as structural motifs are fairly common in pharmacology.

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