Produktname:Pyrido[3,4-b]pyrazine-2,3(1H,4H)-dione

IUPAC Name:1H,2H,3H,4H-pyrido[3,4-b]pyrazine-2,3-dione

CAS:35251-84-4
Molekulare Formel:C7H5N3O2
Reinheit:97%
Katalognummer:CM214023
Molekulargewicht:163.14

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Produkt-Details

CAS-Nr.:35251-84-4
Molekulare Formel:C7H5N3O2
Schmelzpunkt:-
SMILES-Code:O=C1NC=2C=NC=CC2NC1=O
Dichte:
Katalognummer:CM214023
Molekulargewicht:163.14
Siedepunkt:
Mdl-Nr.:MFCD01411816
Lagerung:

Category Infos

Quinazolines
Quinazolines belong to heterocyclic chemistry, also known as 1,3-naphthalenes. The backbone consists of two six-membered aromatic rings fused to each other, with two nitrogen atoms at positions 1 and 3 on the backbone. The presence of these two nitrogen atoms in quinazoline increases its importance in pharmaceutical and biological reactions. Quinazolines and their derivatives are among the most important heterocyclic compounds due to their diverse chemical reactivity and important range of biological activities.

Column Infos

CVN424
In a Phase 2 clinical trial, CVN424, a novel, non-dopaminergic, GPR6 inverse agonist, demonstrated a significant reduction in OFF time and was safe and well tolerated with low rates of mostly mild and moderate adverse events. Patients also reported enhanced motor functionality in daily activities, as assessed by the UPDRS Part II. These findings enhance the confidence in CVN424's potential to address both motor and non-motor symptoms of Parkinson’s disease, consistent with observations in pre-clinical models, potentially heralding a transformative non-dopaminergic therapy.
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