Produktname:cis-N1-Boc-1,2-cyclopentanediamine
IUPAC Name:tert-butyl N-[(1R,2S)-2-aminocyclopentyl]carbamate
Product Overview |
Tert-Butyl ((1R,2S)-2-aminocyclopentyl)carbamate, also known as Boc-aminocyclopentane, is a chemical compound used in scientific research. It is a derivative of cyclopentane and is commonly used as a protecting group for amino acids during peptide synthesis. |
Synthesis Method |
Tert-Butyl ((1R,2S)-2-aminocyclopentyl)carbamate can be synthesized using several methods. One of the most common methods is the reaction of tert-butyl carbamate with (1R,2S)-2-aminocyclopentanol in the presence of a catalyst. Another method involves the reaction of tert-butyl carbamate with (1R,2S)-2-aminocyclopentanone in the presence of a reducing agent. |
Chemical Properties |
It allows for the selective protection of the amino group, which is important for the synthesis of complex peptides. It also allows for the synthesis of peptides with high yields and purity.However, there are also limitations to its use. The removal of the protecting group can be difficult and may require harsh conditions, which can lead to unwanted side reactions. It may also be incompatible with certain reaction conditions, limiting its use in some peptide synthesis reactions. |
Synthesis and Application |
Tert-Butyl ((1R,2S)-2-aminocyclopentyl)carbamate is widely used in scientific research, particularly in peptide synthesis. It is commonly used as a protecting group for amino acids during peptide synthesis. It can also be used as a reagent for the preparation of chiral amines and as a starting material for the synthesis of various biologically active compounds. |
Future Directions |
One direction is the development of new methods for the selective removal of the protecting group. Another direction is the synthesis of new peptides and biologically active compounds using tert-Butyl ((1R,2S)-2-aminocyclopentyl)carbamate as a starting material. Additionally, the use of tert-Butyl ((1R,2S)-2-aminocyclopentyl)carbamate in the synthesis of complex peptides and proteins may have important applications in drug discovery and development. |