Produktname:4-chloro-7H-pyrrolo[2,3-d]pyrimidine

IUPAC Name:4-chloro-7H-pyrrolo[2,3-d]pyrimidine

CAS:3680-69-1
Molekulare Formel:C6H4ClN3
Reinheit:95%+
Katalognummer:CM101908
Molekulargewicht:153.57

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Produkt-Details

CAS-Nr.:3680-69-1
Molekulare Formel:C6H4ClN3
Schmelzpunkt:-
SMILES-Code:ClC1=C2C=CNC2=NC=N1
Dichte:
Katalognummer:CM101908
Molekulargewicht:153.57
Siedepunkt:325.9°C at 760 mmHg
Mdl-Nr.:MFCD01686865
Lagerung:Keep in a dry and a tight container and store at ambient temperature

Category Infos

Pyrrolopyrimidines
Fusion heterocyclic compounds have various biological activities, such as anticancer, antibacterial, antifungal and anti-inflammatory, and thus have been widely used in the field of medicinal chemistry. Pyrrolopyrimidines are a major class of fused heterocyclic compounds. Compared with single pyrrole and pyrimidine cores, pyrrolopyrimidines have more diverse and effective pharmacological characteristics as fusion scaffolds.

Column Infos

Delgocitinib
Positive phase 3 head-to-head data results from DELTA FORCE trial comparing delgocitinib cream with alitretinoin capsules in adults with severe chronic hand eczema (CHE). Delgocitinib cream demonstrated a superior reduction in Hand Eczema Severity Index score from baseline to Week 12 compared to alitretinoin capsules as its primary outcome measure.
Delgocitinib cream is an investigational, first-in-class, topical pan-Janus kinase (JAK) inhibitor for CHE. It inhibits the activation of JAK-STAT signaling, which plays a key role in the pathogenesis of CHE.