Produktname:4-Chloro-2-methoxy-1-methylbenzene

IUPAC Name:4-chloro-2-methoxy-1-methylbenzene

CAS:40794-04-5
Molekulare Formel:C8H9ClO
Reinheit:97%
Katalognummer:CM283380
Molekulargewicht:156.61

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Produkt-Details

CAS-Nr.:40794-04-5
Molekulare Formel:C8H9ClO
Schmelzpunkt:-
SMILES-Code:CC1=CC=C(Cl)C=C1OC
Dichte:
Katalognummer:CM283380
Molekulargewicht:156.61
Siedepunkt:204°C at 760 mmHg
Mdl-Nr.:MFCD07368289
Lagerung:Store at 2-8°C.

Column Infos

Crinecerfont
The New England Journal of Medicine publishes the primary CAHtalyst™ Adult Phase 3 study results of Crinecerfont for the treatment of congenital adrenal hyperplasia (CAH). Classic congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency (21OHD) is a rare genetic disorder, affected by a lack of cortisol and/or aldosterone. Corticotropin-releasing factor type 1 receptor (CRF1) antagonism is shown to clinically decrease ACTH production and adrenal androgen levels.
Neurocrine's Crinecerfont is an investigational, selective CRF1 antagonist being developed to reduce and control excess adrenocorticotropic hormone (ACTH) and adrenal androgens. The phase 3 study meets primary and important key secondary endpoints, including a significant reduction in androstenedione levels and lowering glucocorticoid dosing.