Produktname:2-Bromo-N-(4,5-Dimethylisoxazol-3-Yl)-N-(Methoxymethyl)Benzenesulfonamide
IUPAC Name:2-bromo-N-(4,5-dimethyl-1,2-oxazol-3-yl)-N-(methoxymethyl)benzene-1-sulfonamide
- CAS:415697-57-3
- Molekulare Formel:C13H15BrN2O4S
- Reinheit:95%+
- Katalognummer:CM429843
- Molekulargewicht:375.24
Nur für den Einsatz in Forschung und Entwicklung..
Produkt-Details
- CAS-Nr.:415697-57-3
- Molekulare Formel:C13H15BrN2O4S
- Schmelzpunkt:-
- SMILES-Code:COCN(C1=NOC(C)=C1C)S(=O)(=O)C1=C(Br)C=CC=C1
- Dichte:
- Katalognummer:CM429843
- Molekulargewicht:375.24
- Siedepunkt:
- Mdl-Nr.:MFCD30185863
- Lagerung:
Category Infos
- Isoxazoles
- Isoxazole is a liquid heterocyclic compound C3H3NO isomeric with oxazole and having a penetrating odor like that of pyridine. Isoxazoles belong to an important class of five-membered aromatic heterocycles containing two electronegative heteroatoms, nitrogen and oxygen, in a 1,2-relationship and three regular sp2 carbon atoms. These molecules are found to be key components in various synthetic products in daily use and also present as a pharmacophore essential for biological activity in many drugs and bioactive natural products. In addition, isoxazoles have demonstrated their ability to exhibit hydrogen bond donor/acceptor interactions with a variety of enzymes and receptors.
Column Infos
- Sparsentan
- CSL Vifor and Travere Therapeutics announce European Commission approves FILSPARI(sparsentan) for the treatment of IgA Nephropathy (IgAN). First non-immunosuppressive therapy for the treatment of IgAN approved in Europe.
Sparsentan is a novel, non-immunosuppressive, single-molecule, dual endothelin angiotensin receptor antagonist with high selectivity for the endothelin A receptor (ETAR) and the angiotensin II subtype 1 receptor (AT1R). Pre-clinical data have shown that blockade of both endothelin type A and angiotensin II type 1 pathways in forms of rare chronic kidney disease, protects podocytes, prevents glomerulosclerosis and mesangial cell proliferation, and reduces proteinuria.