Produktname:3-[7-(aminomethyl)-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione;hydrochloride
IUPAC Name:3-[4-(aminomethyl)-1-oxo-2,3-dihydro-1H-isoindol-2-yl]piperidine-2,6-dione hydrochloride
- CAS:444289-05-8
- Molekulare Formel:C14H16ClN3O3
- Reinheit:95%+
- Katalognummer:CM340808
- Molekulargewicht:309.75
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Produkt-Details
- CAS-Nr.:444289-05-8
- Molekulare Formel:C14H16ClN3O3
- Schmelzpunkt:-
- SMILES-Code:O=C(C(N1CC2=C(C=CC=C2CN)C1=O)CC3)NC3=O.[H]Cl
- Dichte:
- Katalognummer:CM340808
- Molekulargewicht:309.75
- Siedepunkt:
- Mdl-Nr.:
- Lagerung:
Category Infos
- PROTAC-E3 Ligase Ligands
- Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
- PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.