Produktname:Ethyl 3-oxopentanoate

IUPAC Name:ethyl 3-oxopentanoate

CAS:4949-44-4
Molekulare Formel:C7H12O3
Reinheit:98%
Katalognummer:CM253179
Molekulargewicht:144.17

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Produkt-Details

CAS-Nr.:4949-44-4
Molekulare Formel:C7H12O3
Schmelzpunkt:-
SMILES-Code:CCC(CC(OCC)=O)=O
Dichte:
Katalognummer:CM253179
Molekulargewicht:144.17
Siedepunkt:193°C at 760 mmHg
Mdl-Nr.:MFCD00009317
Lagerung:Keep in a tight container and store at ambient temperature,protect from light

Column Infos

VX-548
Vertex announced positive results from its Phase 2 dose-ranging study of VX-548 in people with painful diabetic peripheral neuropathy (DPN). VX-548 is an investigational oral, selective NaV1.8 inhibitor that is highly selective for NaV1.8 relative to other NaV channels. NaV1.8 is a voltage-gated sodium channel that plays a critical role in pain signaling in the peripheral nervous system. NaV1.8 is a genetically validated target for the treatment of pain. Vertex's strategy is to develop new drug types by selectively inhibiting NaV1.8. Compared to opioid drugs, they may provide better analgesic effects while avoiding side effects such as addiction. VX-548 has been granted Breakthrough Therapy and Fast Track designations in the U.S. for moderate to severe acute pain.