Produktname:2,5,6-trichloronicotinic acid

IUPAC Name:2,5,6-trichloropyridine-3-carboxylic acid

CAS:54718-39-7
Molekulare Formel:C6H2Cl3NO2
Reinheit:95%+
Katalognummer:CM178138
Molekulargewicht:226.44

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Produkt-Details

CAS-Nr.:54718-39-7
Molekulare Formel:C6H2Cl3NO2
Schmelzpunkt:-
SMILES-Code:OC(=O)C1=CC(Cl)=C(Cl)N=C1Cl
Dichte:
Katalognummer:CM178138
Molekulargewicht:226.44
Siedepunkt:359.1°C at 760 mmHg
Mdl-Nr.:MFCD02070018
Lagerung:Store at 2-8°C.

Category Infos

Pyridines
Pyridine is a six-membered heterocyclic compound containing one nitrogen heteroatom. Pyridine and piperidine are the most frequently occurring heterocyclic building blocks in drug molecules. According to incomplete statistics, there are currently more than 180 drugs containing pyridine or piperidine structure that have been marketed, nearly 1/5 of the drugs approved for marketing in recent years contain these two structures.
Pyridine | C5H5N | Pyridine Supplier/Distributor/Manufacturer - Chemenu
Pyridine,Pyridine Wholesale,Pyridine for Sale,Pyridine Supplier,Pyridine Distributor,Pyridine Manufacturer
Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell.

Column Infos

Glecirasib
On January 20, Jacobio Pharma presents data of glecirasib in patients with pancreatic cancer and other solid tumors at the 2024 ASCO GI. For second-line and above KRAS G12C mutated pancreatic cancer patients, the confirmed objective response rate (cORR) was 41.9% and the disease control rate (DCR) was 93.5%. Glecirasib is a potential best-in-class KRAS G12C allosteric inhibitor with promising early clinical efficacy. Glecirasib can be used as monotherapy to treat non-small cell lung cancer, colorectal cancer and other solid tumors with the KRAS G12C mutation. Combinations of Glecirasib with SHP2i, EGFRi, or PD-1 antibodies is expected to have synergistic efficacy and overcome acquired drug resistance.

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