cas 56341-41-4|| where to buy 5-Fluorooxindole

Produktname:5-Fluorooxindole

IUPAC Name:5-fluoro-2,3-dihydro-1H-indol-2-one

Packungseinheit	Verfügbarer Vorrat	Preis($)
CM148054-100g	in stock	ȌƋſ
CM148054-500g	in stock	ƤƋȱ

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: CAS-Nr.:56341-41-4; Molekulare Formel:C8H6FNO; Schmelzpunkt:-; SMILES-Code:C1=C2C(=CC=C1F)NC(=O)C2; Dichte:

: Katalognummer:CM148054; Molekulargewicht:151.14; Siedepunkt:307.2°C at 760 mmHg; Mdl-Nr.:MFCD02179598; Lagerung:Keep in a tight container and store at ambient temperature

: Indolinones; Indolinone derivatives have in common the presence of a hydrogen bond between the C-2 carbonyl and a hydrogen donor in a side chain, generally a pyrrole ring. Indolinone displays very promising antitumor properties by inhibiting various kinase families.

: Vorolanib; EyePoint Pharmaceuticals announced on December 4th announced positive topline results of its Phase 2 DAVIO 2 trial of EYP-1901, an investigational sustained delivery maintenance treatment for wet age-related macular degeneration (wet AMD) combining vorolanib, a selective tyrosine kinase inhibitor with bioerodible Durasert E™. Vorolanib brings a new mechanistic approach to the treatment of VEGF-mediated retinal diseases as a pan-VEGF receptor blocker, blocking all VEGF isoforms. Vorolanib features reduced off-target binding and at clinically relevant doses does not inhibit Tie-2, a critical pathway associated with vascular stability, which may result in an improved efficacy. Further, in an in-vivo model of retinal detachment, vorolanib demonstrated neuroprotection, and potential antifibrotic benefits.