Produktname:(2R,3R,4S,5R)-2-(6-((Benzo[c][1,2,5]oxadiazol-5-ylmethyl)thio)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
IUPAC Name:(2R,3R,4S,5R)-2-(6-{[(2,1,3-benzoxadiazol-5-yl)methyl]sulfanyl}-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
- CAS:566193-95-1
- Molekulare Formel:C17H16N6O5S
- Reinheit:97%
- Katalognummer:CM267726
- Molekulargewicht:416.41
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Produkt-Details
- CAS-Nr.:566193-95-1
- Molekulare Formel:C17H16N6O5S
- Schmelzpunkt:-
- SMILES-Code:OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C2N=CN=C3SCC4=CC5=NON=C5C=C4)O1)O)O
- Dichte:
- Katalognummer:CM267726
- Molekulargewicht:416.41
- Siedepunkt:
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- Lagerung:
Category Infos
- Purines
- Purines are heterocyclic aromatic compounds composed of linked pyrimidine and imidazole rings. In mammals, purines are most commonly expressed in DNA and RNA (including the purines adenine and guanine), as well as single-molecule nucleotides (adenosine triphosphate (ATP), adenosine diphosphate (ADP), adenosine monophosphate (AMP), cyclic AMP, and to a lesser extent guanosine triphosphate (GTP) and cyclic guanosine monophosphate (cGMP). Purines are also key elements of the following energy metabolism molecules: reduced nicotinamide adenine dinucleotide, nicotinamide adenine dinucleotide phosphate (NADPH), and coenzyme Q. Purines can also act as direct neurotransmitters; for example, adenosine may interact with receptors to modulate cardiovascular and central nervous system (CNS) function.
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- Tetrahydrofurans
- Tetrahydrofuran is a heterocyclic organic compound with the molecular formula C4H8O. Tetrahydrofuran belongs to ethers and is the complete hydrogenation product of furan. It is a colorless, water-miscible organic liquid with small viscosity at normal temperature and pressure. Because of its long liquid range, it is a commonly used medium polar aprotic solvent. Its main use is as a precursor of high molecular polymers.
- Benzofurazans
- Benzofurazans are important pharmaceutical intermediates. Benzofurazans are known bioisosteres of the nitro group. Both oxadiazoles and nitro groups have strong electron-withdrawing properties, but when optimizing drug-like properties such as activity, selectivity, and stability, the absence of standard charges in the oxadiazole structure may be more beneficial to drug products. What's more, nitro groups have been identified as toxic groups, and it is routine to remove or replace them in the early stages of drug development.