cas 58479-61-1||tert-butyl-chloro-diphenylsilane

Produktname:tert-butyl-chloro-diphenylsilane

IUPAC Name:tert-butyl(chloro)diphenylsilane

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: CAS-Nr.:58479-61-1; Molekulare Formel:C16H19ClSi; Schmelzpunkt:-; SMILES-Code:Cl[Si](C1=CC=CC=C1)(C(C)(C)C)C2=CC=CC=C2; Dichte:

: Katalognummer:CM328470; Molekulargewicht:274.86; Siedepunkt:; Mdl-Nr.:; Lagerung:

: Namodenoson; Namodenoson is a small orally bioavailable drug that binds with high affinity and selectivity to the A3 adenosine receptor (A3AR). Namodenoson was evaluated in Phase II trials for two indications, as a second line treatment for hepatocellular carcinoma, and as a treatment for non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH).
Namodenoson granted Orphan Drug and Fast track status from the FDA. A3AR is highly expressed in diseased cells whereas low expression is found in normal cells. This differential effect accounts for the excellent safety profile of the drug.