Produktname:2-amino-N-cyclopropyl-4-phenylthiophene-3-carboxamide

IUPAC Name:2-amino-N-cyclopropyl-4-phenylthiophene-3-carboxamide

CAS:590355-70-7
Molekulare Formel:C14H14N2OS
Reinheit:95%
Katalognummer:CM113877
Molekulargewicht:258.34

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Produkt-Details

CAS-Nr.:590355-70-7
Molekulare Formel:C14H14N2OS
Schmelzpunkt:-
SMILES-Code:O=C(C1=C(N)SC=C1C2=CC=CC=C2)NC3CC3
Dichte:
Katalognummer:CM113877
Molekulargewicht:258.34
Siedepunkt:
Mdl-Nr.:MFCD03945896
Lagerung:

Category Infos

Thiophenes
Thiophene is a five-membered heterocyclic compound containing a sulfur heteroatom with the molecular formula C4H4S. Thiophene is aromatic and is very similar to benzene; electrophilic substitution reaction is easier than benzene, and it is mainly substituted at the 2-position. Thiophene ring system has certain stability to oxidant.
Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

Column Infos

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