IUPAC Name:(2S)-2-[(4-{[(2-amino-4-oxo-4,8-dihydropteridin-6-yl)methyl]amino}phenyl)formamido]-4-{[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-2-carboxy-1-{[(1R)-1-carboxy-2-sulfanylethyl]carbamoyl}ethyl]carbamoyl}butyl]carbamoyl}-2-carboxyethyl]carbamoyl}butanoic acid
- CAS:625827-91-0
- Molekulare Formel:C36H46N14O14S
- Reinheit:95%+
- Katalognummer:CM339213
- Molekulargewicht:930.91
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Produkt-Details
- CAS-Nr.:625827-91-0
- Molekulare Formel:C36H46N14O14S
- Schmelzpunkt:-
- SMILES-Code:O=C1C2=NC(CNC3=CC=C(C(N[C@H](C(O)=O)CCC(N[C@@H](CC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(O)=O)C(N[C@@H](CS)C(O)=O)=O)=O)=O)=O)=O)C=C3)=CNC2=NC(N)=N1
- Dichte:
- Katalognummer:CM339213
- Molekulargewicht:930.91
- Siedepunkt:
- Mdl-Nr.:
- Lagerung:
Category Infos
- Non-cleavable linkers
- Noncleavable linkers consist of stable bonds that resist proteolytic degradation and provide higher stability than the cleavable linkers.
- ADC Linker-payload Complexes
- Linker-payload complexes consist of two parts: a highly toxic drug which is a small molecule that interacts with intracellular targets and functions as agents to block or disrupt crucial cellular metabolic pathways and eventually lead to cell death, and a linker that facilitates the conjugation of ADC toxins to antibodies and in the meantime, dictates the release mechanism of an ADC.