Produktname:3-Bromopiperidine-2,6-dione

IUPAC Name:3-bromopiperidine-2,6-dione

CAS:62595-74-8
Molekulare Formel:C5H6BrNO2
Reinheit:98%
Katalognummer:CM143204
Molekulargewicht:192.01

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Produkt-Details

CAS-Nr.:62595-74-8
Molekulare Formel:C5H6BrNO2
Schmelzpunkt:-
SMILES-Code:O=C(C(Br)CC1)NC1=O
Dichte:1.748g/cm3
Katalognummer:CM143204
Molekulargewicht:192.01
Siedepunkt:336.4°C at 760 mmHg
Mdl-Nr.:MFCD11053059
Lagerung:Keep in a tight container and store at 2°C~8°C

Category Infos

Piperidines
Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
Piperidine,Piperidine Price
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Column Infos

KT-474
Kymera announced that the first patient has been dosed in the randomized Phase 2 clinical trial in hidradenitis suppurativa (HS) evaluating KT-474 (SAR444656). The Phase 2 study will evaluate the efficacy, safety, pharmacokinetics, and biological effects of KT-474 compared with placebo in adult patients with moderate to severe HS. Kymera's partner Sanofi is conducting the Phase 2 study in HS, and has initiated a second randomized Phase 2 trial in AD. Under the terms of the collaboration, dosing of the first patient in the HS trial generated a milestone payment of $40 million. KT-474 is an oral IRAK4 degrader, in development for the treatment of IL-1R/TLR-driven complex inflammatory diseases where there is an opportunity to significantly advance the standard of care, including HS and AD. Sanofi, which is collaborating with Kymera on the development of KT-474 outside of the oncology and immune-oncology fields, is conducting the Phase 2 studies.
Chemenu has been working to develop more compounds for drug discovery. Here are the building blocks we can provide.
CFT7455
C4 Therapeutics recently announces positive results from initial study of CFT7455 in Relapsed/Refractory Multiple Myeloma (R/R MM). CFT7455 is a potent, selective MonoDAC (Monofunctional Degradation Activating Compound) degrader of IKZF1/3 gene. It binds to cereblon (CRBN) E3 ligase with high affinity in Multiple Myeloma and Non-Hodgkin Lymphoma. CFT7455 can act as a single agent or in combination with Dexamethasone for R/R MM patients.