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  2. Category: Cyclopropanes
  3. product Cas No.: 67376-94-7

Produktname:N-methylcyclopropanamine hydrochloride

IUPAC Name:N-methylcyclopropanamine hydrochloride

CAS：67376-94-7
Molekulare Formel：C4H10ClN
Reinheit：95%+
Katalognummer：CM105051
Molekulargewicht：107.58
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Produkt-Details

CAS-Nr.:67376-94-7
Molekulare Formel:C4H10ClN
Schmelzpunkt:-
SMILES-Code:Cl.CNC1CC1
Dichte:
Katalognummer:CM105051
Molekulargewicht:107.58
Siedepunkt:
Mdl-Nr.:MFCD09997746
Lagerung:

Category Infos

Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

Column Infos

Cyclanes
Cyclanes are secondary metabolites that can be found in plants, and are also biochemicals that can be used in medicine. Cyclanes are found in pine trees, and are used in the making of plastics. Cyclenes are found in cinnamon, and have antifungal properties.

Product Other Information

Product Overview N-methylcyclopropanamine hydrochloride is an organic compound that is widely used in scientific research. It is a derivative of cyclopropane and is an important intermediate in organic synthesis. It is a versatile compound with a wide range of applications in the fields of chemical synthesis, analytical chemistry, and biochemistry.
Physical Properties N-methylcyclopropanamine hydrochloride is a colorless, odorless, and hygroscopic solid that is soluble in polar solvents such as water and alcohols.
Chemical Properties N-methylcyclopropanamine hydrochloride is a reactive compound, often utilized as a starting material or intermediate in various chemical reactions and synthesis processes.
Synthesis and Application N-methylcyclopropanamine hydrochloride is an important reagent in organic synthesis and is used to form a variety of substituted cyclopropanes. It is also used in the synthesis of cyclopropane-containing drugs, such as the anti-cancer drug cabazitaxel. In addition, N-methylcyclopropanamine hydrochloride is used as a reagent in the synthesis of other organic compounds, such as cyclopropyl amines, cyclopropyl nitriles, and cyclopropyl carboxylic acids.
In analytical chemistry, N-methylcyclopropanamine hydrochloride is used as a derivatizing agent in gas chromatography–mass spectrometry (GC–MS) and liquid chromatography–mass spectrometry (LC–MS) for the detection and quantification of various compounds. It is also used in the analysis of amino acids, peptides, and proteins by mass spectrometry.
In biochemistry, N-methylcyclopropanamine hydrochloride is used as a substrate for the enzyme cyclopropane-fatty-acyl-phospholipase D (CP-PLD). It is also used to study the structure and function of cyclopropane-containing lipids and proteins.
Storage and Handling Store N-methylcyclopropanamine hydrochloride under inert atmosphere at room temperature.