cas 680-15-9|| where to buy methyl 2,2-difluoro-2-fluorosulfonylacetate

Produktname:methyl 2,2-difluoro-2-fluorosulfonylacetate

IUPAC Name:methyl 2,2-difluoro-2-(fluorosulfonyl)acetate

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CM333421-1000g	in stock	ȌȦǆ

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: CAS-Nr.:680-15-9; Molekulare Formel:C3H3F3O4S; Schmelzpunkt:-; SMILES-Code:O=C(OC)C(F)(F)S(=O)(F)=O; Dichte:

: Katalognummer:CM333421; Molekulargewicht:192.11; Siedepunkt:; Mdl-Nr.:MFCD00144316; Lagerung:Keep in a tight container and store at 2°C~8°C

: Aliphatic Chain Compounds; Aliphatic chain compounds include aliphatic compounds and chain compounds containing other elements or groups. Aliphatic hydrocarbons are hydrocarbons with the basic properties of aliphatic compounds. In aliphatic compounds, carbon atoms are arranged in straight chain, branched chain or cyclic, which are respectively called straight chain aliphatic hydrocarbons, branched chain aliphatic hydrocarbons and alicyclic hydrocarbons. Some cyclic hydrocarbons are different in nature from aromatic hydrocarbons, and are very similar to aliphatic hydrocarbons. Such cyclic hydrocarbons are called alicyclic hydrocarbons. In this way, aliphatic hydrocarbons become a general term for all hydrocarbons except aromatic hydrocarbons. Aliphatic hydrocarbons and their derivatives (including halogenated hydrocarbons) and alicyclic hydrocarbons and their derivatives are collectively referred to as aliphatic compounds.

: LTGO-33; Voltage-gated sodium channels (NaVs) are responsible for action potential initiation and transmission of pain signals. NaV1.8 is specifically expressed in peripheral nociceptors and has been genetically and pharmacologically validated as a human pain target.
LTGO-33 inhibited NaV1.8 in the nM potency range and exhibited over 600-fold selectivity against human NaV1.1-NaV1.7 and NaV1.9. Unlike prior reported NaV1.8 inhibitors that preferentially interacted with an inactivated state via the pore region, LTGO-33 was state-independent with similar potencies against closed and inactivated channels.