Produktname:SPDP (SPDP Crosslinker)

IUPAC Name:2,5-dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)propanoate

CAS:68181-17-9
Molekulare Formel:C12H12N2O4S2
Reinheit:95%+
Katalognummer:CM191576
Molekulargewicht:312.36

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Produkt-Details

CAS-Nr.:68181-17-9
Molekulare Formel:C12H12N2O4S2
Schmelzpunkt:-
SMILES-Code:O=C(ON1C(CCC1=O)=O)CCSSC2=NC=CC=C2
Dichte:
Katalognummer:CM191576
Molekulargewicht:312.36
Siedepunkt:465.9°C at 760 mmHg
Mdl-Nr.:MFCD00009636
Lagerung:Keep in dark place, inert atmosphere, store in freezer, under -20°C.

Category Infos

Pyridines
Pyridine is a six-membered heterocyclic compound containing one nitrogen heteroatom. Pyridine and piperidine are the most frequently occurring heterocyclic building blocks in drug molecules. According to incomplete statistics, there are currently more than 180 drugs containing pyridine or piperidine structure that have been marketed, nearly 1/5 of the drugs approved for marketing in recent years contain these two structures.
Pyridine | C5H5N | Pyridine Supplier/Distributor/Manufacturer - Chemenu
Pyridine,Pyridine Wholesale,Pyridine for Sale,Pyridine Supplier,Pyridine Distributor,Pyridine Manufacturer
Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell.
Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.
ADC-Linkers
The ADC linker is one of the three main components of antibody drug conjugates (ADCs), linking the antibody to the effective drug (payload) through chemical bonds. ADC linkers play a key role in determining the overall success of antibody drug conjugates. One of the major challenges in developing safe and effective ADC drugs is to assemble an ideal chemical linker between the cytotoxic payload and the mAb. Well-designed ADC linkers can help the selective delivery of antibodies at the tumor site and the accurate release of cytotoxic drugs.
Cleavable linkers
Cleavable linkers rely on the inherent properties of a cell’s cytoplasmic compartments for selective release of the cytotoxic drug.
N-Hydroxysuccinimide (NHS)
N-Hydroxysuccinimide
Disulfides/Thiols
In chemistry, a disulfide is a compound containing a R−S−S−R′ functional group or the S 2− anion. Thiols are the sulfur analogue of alcohols.

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