Produktname:1-(4-aminophenyl)-3-methyl-hexahydropyrimidine-2,4-dione

IUPAC Name:1-(4-aminophenyl)-3-methyl-1,3-diazinane-2,4-dione

CAS:791021-42-6
Molekulare Formel:C11H13N3O2
Reinheit:95%
Katalognummer:CM1076824
Molekulargewicht:219.24

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Produkt-Details

CAS-Nr.:791021-42-6
Molekulare Formel:C11H13N3O2
Schmelzpunkt:-
SMILES-Code:CN1C(=O)CCN(C1=O)C1=CC=C(N)C=C1
Dichte:
Katalognummer:CM1076824
Molekulargewicht:219.24
Siedepunkt:
Mdl-Nr.:
Lagerung:

Category Infos

PROTAC-E3 Ligase Ligands
Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.