Produktname:3-Hydrazino-6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazine

IUPAC Name:5-hydrazinyl-3,4-diazatricyclo[9.4.0.0²,⁷]pentadeca-1(15),2,4,6,11,13-hexaene

CAS:802598-74-9
Molekulare Formel:C13H14N4
Reinheit:95%+
Katalognummer:CM337866
Molekulargewicht:226.28

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Produkt-Details

CAS-Nr.:802598-74-9
Molekulare Formel:C13H14N4
Schmelzpunkt:-
SMILES-Code:NNC1=NN=C2C(CCCC3=CC=CC=C32)=C1
Dichte:
Katalognummer:CM337866
Molekulargewicht:226.28
Siedepunkt:
Mdl-Nr.:
Lagerung:2-8ºC

Column Infos

Bemcentinib
Bemcentinib is a potentially first-in-class selective AXL inhibitor in development for STK11 mutated NSCLC and severe respiratory infections. Extensive studies confirm the ability to combine bemcentinib with immune checkpoint inhibitors, chemotherapies and targeted therapies with the goal of improving a patient’s immune response and delaying the development of chemoresistance. Bemcentinib is currently being investigated in combination with immune checkpoint inhibition and chemotherapy in first line NSCLC patients harboring mutations in the STK11 gene, a known prognostic factor of poor response to existing therapies.

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