Produktname:prop-2-enoyl chloride
IUPAC Name:prop-2-enoyl chloride
- CAS:814-68-6
- Molekulare Formel:C3H3ClO
- Reinheit:95%+
- Katalognummer:CM350755
- Molekulargewicht:90.51
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Produkt-Details
- CAS-Nr.:814-68-6
- Molekulare Formel:C3H3ClO
- Schmelzpunkt:-
- SMILES-Code:C=CC(Cl)=O
- Dichte:
- Katalognummer:CM350755
- Molekulargewicht:90.51
- Siedepunkt:
- Mdl-Nr.:
- Lagerung:Keep in a tight container and store at 2°C~8°C,protect from light
Column Infos
- MK-1084
- Merck initiates Phase 3 clinical trial of MK-1084, an investigational oral KRAS G12C inhibitor, in combination with KEYTRUDA® (pembrolizumab) for first-line treatment of certain patients with metastatic non-small cell lung cancer. KRAS mutations are one of the most frequently observed mutations in human cancers, making them a crucial target for precision oncology therapy.
MK-1084 is an investigational, oral covalent inhibitor of KRAS G12C, that is found in about 14% of people with non-small cell lung cancer. MK-1084 is currently under Phase 1 evaluation as monotherapy and as combined therapies in patients with KRAS G12C mutant advanced solid tumors.