Produktname:(R)-O-ISOPROPYLIDENE GLYCEROL MESYLATE
IUPAC Name:[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl methanesulfonate
- CAS：83461-40-9
- Molekulare Formel：C7H14O5S
- Reinheit：95%+
- Katalognummer：CM1032311
- Molekulargewicht：210.24
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Produkt-Details
- CAS-Nr.:83461-40-9
- Molekulare Formel:C7H14O5S
- Schmelzpunkt:-
- SMILES-Code:CC1(OC[C@@H](O1)COS(=O)(=O)C)C
- Dichte:
- Katalognummer:CM1032311
- Molekulargewicht:210.24
- Siedepunkt:
- Mdl-Nr.:
- Lagerung:
Category Infos
- Dioxolanes
- Dioxolane is a heterocyclic acetal with the formula (CH2)2O2CH2. It is related to tetrahydrofuran by exchanging an oxygen for the CH2 group. The isomer 1,2-dioxolane (in which the two oxygen centers are adjacent) is a peroxide. 1,3-Dioxolane is used as solvent and comonomer in polyacetal. The dioxolane-type and their hydrogenolysis can provide very valuable partially protected building blocks either for oligosaccharide syntheses or sugar transformations.
Column Infos
- Mirdametinib
- SpringWorks Therapeutics announced that the Company has initiated a rolling submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for mirdametinib, an investigational MEK inhibitor, in pediatric and adult patients with neurofibromatosis type 1-associated plexiform neurofibromas (NF1-PN). The NDA submission includes data from the Phase 2b ReNeu trial. The primary endpoint was confirmed objective response rate (ORR). The BICR-confirmed objective response rate was 52% in pediatric patients and 41% in adult patients. Mirdametinib treatment showed deep and durable responses and demonstrated significant improvements in key secondary patient-reported outcome measures.
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