Produktname:2-(2,6-dioxopiperidin-3-yl)-5-fluoroisoindole-1,3-dione

IUPAC Name:2-(2,6-dioxopiperidin-3-yl)-5-fluoro-2,3-dihydro-1H-isoindole-1,3-dione

CAS:835616-61-0
Molekulare Formel:C13H9FN2O4
Reinheit:95%+
Katalognummer:CM338817
Molekulargewicht:276.22

Packungseinheit Verfügbarer Vorrat Preis($) Menge
CM338817-5g in stock ƥȯ
CM338817-10g in stock Şǫǫ
CM338817-25g in stock ȯǫƥ

Nur für den Einsatz in Forschung und Entwicklung..

Anfrage-Formular

   refresh    

Produkt-Details

CAS-Nr.:835616-61-0
Molekulare Formel:C13H9FN2O4
Schmelzpunkt:-
SMILES-Code:O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC(F)=C3)=O
Dichte:
Katalognummer:CM338817
Molekulargewicht:276.22
Siedepunkt:
Mdl-Nr.:
Lagerung:

Category Infos

PROTAC-E3 Ligase Ligands
Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.

Column Infos

E3 ligase ligand
E3 ligase ligand is an important biochemical molecule, which plays an important role in cells. It can bind to E3 ligase, thus promoting protein degradation and cell metabolism. In vivo, the stability and activity of E3 ligase ligands are very important for the normal function of cells. Studies have shown that E3 ligase ligands play an important role in cell cycle, apoptosis, DNA repair and other aspects.