Produktname:(1S,3S,4S,5R)-2-tert-butoxycarbonyl-5-hydroxy-2-azabicyclo[2.2.2]octane-3-carboxylic acid
IUPAC Name:(1S,3S,4S,5R)-2-[(tert-butoxy)carbonyl]-5-hydroxy-2-azabicyclo[2.2.2]octane-3-carboxylic acid
- CAS：851389-23-6
- Molekulare Formel：C13H21NO5
- Reinheit：95%+
- Katalognummer：CM1018411
- Molekulargewicht：271.31
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Produkt-Details
- CAS-Nr.:851389-23-6
- Molekulare Formel:C13H21NO5
- Schmelzpunkt:-
- SMILES-Code:CC(C)(C)OC(=O)N1[C@H]2CC[C@@H]([C@H]1C(=O)O)[C@H](O)C2
- Dichte:
- Katalognummer:CM1018411
- Molekulargewicht:271.31
- Siedepunkt:
- Mdl-Nr.:
- Lagerung:
Category Infos
- Piperidines
- Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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- Cyclohexanes
- Cyclohexane is an organic compound with a chemical formula C6H12. It is a colorless liquid with a pungent odor, insoluble in water, and soluble in most organic solvents such as ethanol, ether, benzene, and acetone. Cyclohexyl fragments are a common structure in both natural and synthetic drugs. It can be used as both core structure and part of achiral side chain.
Column Infos
- DSP-5336
- Sumitomo Pharma announces that DSP-5336 has received FDA Fast Track Designation for the treatment of relapsed or refractory acute myeloid leukemia (AML) with a KMT2A rearrangement, also known as, mixed lineage leukemia rearrangement (MLLr) or nucleophosmin mutation (NPM1m). Menin serves as a tumor suppressor in endocrine glands. Novel menin inhibitors are novel targeted agents in clinical studies targeting genetically defined subsets of acute leukemia.
DSP-5336 is an investigational menin-MLL interaction inhibitor. DSP-5336 has been granted Orphan Drug Designation in acute myeloid leukemia, and Fast Track Designation in relapsed or refractory acute myeloid leukemia with MLLr or NPM1m.
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