Produktname:Methyl 2-methyl-2-(4-nitro-1H-imidazol-1-yl)propanoate
IUPAC Name:methyl 2-methyl-2-(4-nitro-1H-imidazol-1-yl)propanoate
- CAS：865774-07-8
- Molekulare Formel：C8H11N3O4
- Reinheit：95%+
- Katalognummer：CM330792
- Molekulargewicht：213.19
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Produkt-Details
- CAS-Nr.:865774-07-8
- Molekulare Formel:C8H11N3O4
- Schmelzpunkt:-
- SMILES-Code:O=[N+](C1=CN(C(C(OC)=O)(C)C)C=N1)[O-]
- Dichte:
- Katalognummer:CM330792
- Molekulargewicht:213.19
- Siedepunkt:
- Mdl-Nr.:
- Lagerung:
Category Infos
- Imidazoles
- Imidazole is an important five-membered nitrogen-containing heterocyclic compound. Among the numerous heterocyclic compounds, imidazole and its derivatives are regarded as a unique and multifaceted scaffold material due to their diverse applications in industrial, organic and pharmaceutical chemistry. Imidazoles interact in different ways with many therapeutic targets, enzymes and receptors in biological systems and thus exhibit a wide range of biological activities. In particular, several imidazoles can be used as clinical drugs to treat various types of cancer with high therapeutic efficacy. Furthermore, imidazoles are one of the most critical segments in the field of anti-covid-19 virus drug discovery due to their ability to interact with active targets in living systems.
- Imidazole Manufacturer
- As a professional imidazole manufacturer, we can guarantee product quality and delivery time.our company has been committed to supply personalized product solutions to customers,pls consult us.
Column Infos
- Ogsiveo
- The FDA has approved Ogsiveo (Nirogacestat) tablets for adult patients with progressing desmoid tumors who require systemic treatment. Ogsiveo is the first drug to be approved for the treatment of patients with desmoid tumors, a rare subtype of soft tissue sarcomas. The FDA approval of Ogsiveo is based on the results from the Phase 3 DeFi trial. The results showed that Ogsiveo met the primary endpoint of improving progression-free survival (PFS), demonstrating a statistically significant improvement over placebo with a 71% reduction in the risk of disease progression (hazard ratio (HR) = 0.29 (95% CI: 0.15, 0.55); p< 0.001). Ogsiveo is an oral, selective, small molecule gamma secretase inhibitorγ. Gamma secretase cleaves multiple transmembrane proteins, including Notch, that are believed to play a role in activating pathways that contribute to growth of desmoid and ovarian granulosa cell tumors.
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