Produktname:2-Benzyloctahydropyrrolo[3,4-c]pyrrole
IUPAC Name:2-benzyl-octahydropyrrolo[3,4-c]pyrrole
- CAS：86732-22-1
- Molekulare Formel：C13H18N2
- Reinheit：95%+
- Katalognummer：CM121905
- Molekulargewicht：202.3
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Produkt-Details
- CAS-Nr.:86732-22-1
- Molekulare Formel:C13H18N2
- Schmelzpunkt:-
- SMILES-Code:N1(CC2=CC=CC=C2)CC(CNC3)C3C1
- Dichte:
- Katalognummer:CM121905
- Molekulargewicht:202.3
- Siedepunkt:
- Mdl-Nr.:MFCD04115126
- Lagerung:Store at 2-8°C.
Category Infos
- Pyrrolidines
- Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.
Column Infos
- Alicyclic Heterocycles
- When the ends of the chains are joined together into a ring, cyclic compounds result; such substances often are referred to as carbocyclic or alicyclic compounds. Substitution of one or more of the ring carbon atoms in the molecules of a carbocyclic compound with a heteroatom gives a heterocyclic compound.
- Benzenes
- Benzene is an important organic compound with the chemical formula C6H6, and its molecule consists of a ring of 6 carbon atoms, each with 1 hydrogen atom. Benzene is a sweet, flammable, colorless and transparent liquid with carcinogenic toxicity at room temperature, and has a strong aromatic odor. It is insoluble in water, easily soluble in organic solvents, and can also be used as an organic solvent itself. The ring system of benzene is called benzene ring, and the structure after removing one hydrogen atom from the benzene ring is called phenyl. Benzene is one of the most important basic organic chemical raw materials. Many important chemical intermediates can be derived from benzene through substitution reaction, addition reaction and benzene ring cleavage reaction.
- Seltorexant
- Johnson & Johnson pivotal study of Seltorexant shows statistically significant and clinically meaningful improvement in depressive symptoms and sleep disturbance outcomes. Seltorexant meets all primary and secondary endpoints in the pivotal Phase 3 MDD3001 clinical trial of adult and elderly patients with major depressive disorder (MDD) with insomnia symptoms.
Orexin signaling pathways are found to be associated with depression and anxiety. Orexin neurons receive and transmit signals throughout the central nervous system (CNS) that are modulated by their specific receptors (OX1R, OX2R). Seltorexant is an investigational first-in-class selective antagonist of ORX2 receptor. It is developed as an adjunctive therapy for MDD and for the treatment of insomnia disorder.
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