cas 876343-10-1|| where to buy 4-chloro-6-iodo-7H-pyrrolo[2,3-d]pyrimidine

Produktname:4-chloro-6-iodo-7H-pyrrolo[2,3-d]pyrimidine

IUPAC Name:4-chloro-6-iodo-7H-pyrrolo[2,3-d]pyrimidine

Packungseinheit	Verfügbarer Vorrat	Preis($)
CM104043-5g	in stock	ŤľŮ
CM104043-10g	in stock	ƈƥǙ
CM104043-25g	in stock	ľƥŮ

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: CAS-Nr.:876343-10-1; Molekulare Formel:C6H3ClIN3; Schmelzpunkt:-; SMILES-Code:ClC1=C2C=C(I)NC2=NC=N1; Dichte:

: Katalognummer:CM104043; Molekulargewicht:279.47; Siedepunkt:; Mdl-Nr.:MFCD11518919; Lagerung:-20°C

: Pyrrolopyrimidines; Fusion heterocyclic compounds have various biological activities, such as anticancer, antibacterial, antifungal and anti-inflammatory, and thus have been widely used in the field of medicinal chemistry. Pyrrolopyrimidines are a major class of fused heterocyclic compounds. Compared with single pyrrole and pyrimidine cores, pyrrolopyrimidines have more diverse and effective pharmacological characteristics as fusion scaffolds.

: BMF-219; Biomea Fusion’s BMF-219 demonstrates promising early signs of clinical activity, with its ability to achieve durable and sustained complete responses (CRs) and minimal residual disease negativity (MRD-neg) in patients with acute myeloid leukemia (AML). Biomea Fusion recently presents this First Complete Responder from Ongoing Phase I Study at the 2023 ASH.
BMF-219 is the first and only covalent menin inhibitor in clinical development for AML, ALL, DLBCL, MM and CLL. Additionally, BMF-219 is being explored for its potential to regenerate insulin-producing beta cells as a treatment of type 1 diabetes.