Produktname:2-[4-(azepane-1-sulfonyl)phenyl]-5-(1,2,3,4-tetrahydroisoquinolin-2-yl)-1,3-oxazole-4-carbonitrile
IUPAC Name:2-[4-(azepane-1-sulfonyl)phenyl]-5-(1,2,3,4-tetrahydroisoquinolin-2-yl)-1,3-oxazole-4-carbonitrile
- CAS:940999-71-3
- Molekulare Formel:C25H26N4O3S
- Reinheit:95%+
- Katalognummer:CM835684
- Molekulargewicht:462.57
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Produkt-Details
- CAS-Nr.:940999-71-3
- Molekulare Formel:C25H26N4O3S
- Schmelzpunkt:-
- SMILES-Code:O=S(=O)(N1CCCCCC1)C1=CC=C(C=C1)C1=NC(C#N)=C(O1)N1CCC2=C(C1)C=CC=C2
- Dichte:
- Katalognummer:CM835684
- Molekulargewicht:462.57
- Siedepunkt:
- Mdl-Nr.:
- Lagerung:
Category Infos
- Oxazoles
- Oxazoles are heterocyclic aromatic compounds containing one oxygen atom and one nitrogen atom, separated by a carbon atom. The presence of two heteroatoms (oxygen and nitrogen) provides possible interactions (hydrogen, hydrophobic, van der Waals or dipole bonds) with a wide range of receptors and enzymes. Oxazole rings are valuable heterocyclic scaffolds for the design of novel therapeutics with anticancer, antiviral, antibacterial, anti-inflammatory, neuroprotective, antidiabetic, and antidepressant properties due to their wide range of targets and biological activities.
- Tetrahydroisoquinolines
- Tetrahydroisoquinoline is an organic compound with the chemical formula C9H11N. It is classified as a secondary amine, obtained from isoquinoline by hydrogenation. The tetrahydroisoquinoline moiety forms the backbone of several natural, synthetic and semi-synthetic drugs approved for the treatment of cancer, pain, gout and various neurodegenerative diseases.
- Azepanes
- The use of azepane as a scaffold for drug discovery remains of interest. The azepane linker is the key to efficient activity. A number of seven-membered ring derivatives have been prepared or investigated for their potential or actual pharmacological properties. Examples include azaalkane derivatives as PKB (protein kinase B) inhibitors.