Produktname:N-[(furan-2-yl)methyl]-2-{[2-(morpholin-4-yl)quinolin-8-yl]oxy}acetamide
IUPAC Name:N-[(furan-2-yl)methyl]-2-{[2-(morpholin-4-yl)quinolin-8-yl]oxy}acetamide
- CAS:941903-33-9
- Molekulare Formel:C20H21N3O4
- Reinheit:95%+
- Katalognummer:CM979264
- Molekulargewicht:367.41
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Produkt-Details
- CAS-Nr.:941903-33-9
- Molekulare Formel:C20H21N3O4
- Schmelzpunkt:-
- SMILES-Code:O=C(COC1=CC=CC2=CC=C(N=C12)N1CCOCC1)NCC1=CC=CO1
- Dichte:
- Katalognummer:CM979264
- Molekulargewicht:367.41
- Siedepunkt:
- Mdl-Nr.:
- Lagerung:
Category Infos
- Furans
- Furan is a cyclic flammable liquid compound C4H4O that is obtained from wood oils of pines or made synthetically and is used especially in organic synthesis. Furan is aromatic because a pair of lone pair electrons of the oxygen atom in its molecule forms a large π bond in the plane of the conjugated orbital, making a total of 6 electrons in the plane of the conjugated plane, conforming to the 4n+2 structure. Aromaticity makes furan have the property of easy substitution and difficult addition. The other lone pair of electrons in oxygen stretches out. The oxygen atom itself conforms to sp2 hybridization. Due to the presence of the aromatic ring, the chemical behavior of furan is not very similar to that of other unsaturated heterocycles. The oxygen in the aromatic ring has an electron-donating effect, so the electrophilic substitution reactivity of furan is stronger than that of benzene.
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- Morpholines
- Morpholine contains secondary amine groups and has all the typical reactive characteristics of secondary amine groups. It can react with inorganic acids to form salts, and react with organic acids to form salts or amides, which can be subjected to alkylation reaction, and can also be reacted with ethylene oxide, ketone or Willgerodt reaction. Morpholine is a six-membered ring containing oxygen and nitrogen, and its alkalinity is much lower than that of its parent piperidine. The marketed morpholine drugs are mainly distributed in the fields of tumors, cardiovascular and cerebrovascular diseases, respiratory system diseases, digestive system diseases, infectious diseases and mental disorders.
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- Quinolines
- Quinolines are an important class of biologically active heterocyclic compounds, and their derivatives usually exhibit a variety of biological activities. They can be used as antimalarial drugs and in the preparation of other antimalarial drugs. Other important activities of quinoline derivatives include inhibitory activity against EGFR-TK and antipsychotic activity. Futhermore, quinoline scaffolds are present in various drug molecules, including the antimalarial drugs aablaquine, chloroquine, mefloquine and primaquine, and the antibacterial agents gatifloxacin, levofloxacin, and moxifloxacin.
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