Produktname:3-cyclopropyl-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazine

IUPAC Name:3-cyclopropyl-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazine

CAS:945262-32-8
Molekulare Formel:C8H12N4
Reinheit:95%+
Katalognummer:CM109168
Molekulargewicht:164.21

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Produkt-Details

CAS-Nr.:945262-32-8
Molekulare Formel:C8H12N4
Schmelzpunkt:-
SMILES-Code:C12=NN=C(C3CC3)N1CCNC2
Dichte:
Katalognummer:CM109168
Molekulargewicht:164.21
Siedepunkt:
Mdl-Nr.:MFCD09743508
Lagerung:

Category Infos

Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.