Produktname:1H-Benzotriazole
IUPAC Name:1H-1,2,3-benzotriazole
- CAS:95-14-7
- Molekulare Formel:C6H5N3
- Reinheit:98%
- Katalognummer:CM158391
- Molekulargewicht:119.13
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Produkt-Details
- CAS-Nr.:95-14-7
- Molekulare Formel:C6H5N3
- Schmelzpunkt:-
- SMILES-Code:N1=NC=2C=CC=CC2N1
- Dichte:
- Katalognummer:CM158391
- Molekulargewicht:119.13
- Siedepunkt:
- Mdl-Nr.:MFCD00005699
- Lagerung:Store at room temperature.
Category Infos
- Benzotriazoles
- Benzotriazole is a bicyclic nitrogen heterocycle formed by the fusion of the benzene ring with the 4,5-positions or the “d” site of 1H-1,2,3-triazole. The benzotriazoles are known as important intermediates in the preparation of organic products such as β-amido ketones, aldehydes, β-ketoesters, ionic liquid, and as reagents for acylation and thioacylation reactions. 1H-Benzotriazoles are also known to exhibit broad spectrum of pharmacological activities. There are numerous benzotriazole-based clinically used drugs in the market for the treatment of various diseases.
Column Infos
- Obicetrapib
- The elevated low-density lipoprotein cholesterol (LDL-C) is a causal risk factor for atherosclerotic cardiovascular disease (ASCVD), and heterozygous familial hypercholesterolemia (HeFH). Cholesteryl ester transfer protein (CETP) transports cholesterol from good high-density lipoprotein cholesterol (HDL-C) to low-density lipoprotein cholesterol (LDL-C). NewAmsterdam’s Obicetrapib is a novel, selective CETP inhibitor to address the limitations of current treatments.
Obicetrapib is under investigation in phase III clinical trials as a monotherapy product, and in phase II studies as a fixed dose combination with Ezetimibe.