Produktname:Bis-SS-C3-sulfo-NHS ester

IUPAC Name:1-{[4-({4-[(2,5-dioxo-3-sulfopyrrolidin-1-yl)oxy]-4-oxobutyl}disulfanyl)butanoyl]oxy}-2,5-dioxopyrrolidine-3-sulfonic acid

CAS:98604-89-8
Molekulare Formel:C16H20N2O14S4
Reinheit:95%+
Katalognummer:CM339112
Molekulargewicht:592.58

Packungseinheit Verfügbarer Vorrat Preis($) Menge

Nur für den Einsatz in Forschung und Entwicklung..

Anfrage-Formular

   refresh    

Produkt-Details

CAS-Nr.:98604-89-8
Molekulare Formel:C16H20N2O14S4
Schmelzpunkt:-
SMILES-Code:O=S(C(C1)C(N(OC(CCCSSCCCC(ON2C(C(S(=O)(O)=O)CC2=O)=O)=O)=O)C1=O)=O)(O)=O
Dichte:
Katalognummer:CM339112
Molekulargewicht:592.58
Siedepunkt:
Mdl-Nr.:
Lagerung:

Category Infos

ADC-Linkers
The ADC linker is one of the three main components of antibody drug conjugates (ADCs), linking the antibody to the effective drug (payload) through chemical bonds. ADC linkers play a key role in determining the overall success of antibody drug conjugates. One of the major challenges in developing safe and effective ADC drugs is to assemble an ideal chemical linker between the cytotoxic payload and the mAb. Well-designed ADC linkers can help the selective delivery of antibodies at the tumor site and the accurate release of cytotoxic drugs.
Cleavable linkers
Cleavable linkers rely on the inherent properties of a cell’s cytoplasmic compartments for selective release of the cytotoxic drug.
N-Hydroxysuccinimide (NHS)
N-Hydroxysuccinimide
Disulfides/Thiols
In chemistry, a disulfide is a compound containing a R−S−S−R′ functional group or the S 2− anion. Thiols are the sulfur analogue of alcohols.