Produktname:Folate-PEG3-amine
IUPAC Name:(2S)-2-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)formamido]-4-[(2-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}ethyl)carbamoyl]butanoic acid
- CAS:710323-40-3
- Molekulare Formel:C27H37N9O8
- Reinheit:95%+
- Katalognummer:CM339077
- Molekulargewicht:615.65
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Produkt-Details
- CAS-Nr.:710323-40-3
- Molekulare Formel:C27H37N9O8
- Schmelzpunkt:-
- SMILES-Code:O=C(O)[C@@H](NC(C1=CC=C(NCC2=CN=C3NC(N)=NC(C3=N2)=O)C=C1)=O)CCC(NCCOCCOCCOCCN)=O
- Dichte:
- Katalognummer:CM339077
- Molekulargewicht:615.65
- Siedepunkt:
- Mdl-Nr.:
- Lagerung:
Category Infos
- Non-cleavable linkers
- Noncleavable linkers consist of stable bonds that resist proteolytic degradation and provide higher stability than the cleavable linkers.
- ADC Linker-payload Complexes
- Linker-payload complexes consist of two parts: a highly toxic drug which is a small molecule that interacts with intracellular targets and functions as agents to block or disrupt crucial cellular metabolic pathways and eventually lead to cell death, and a linker that facilitates the conjugation of ADC toxins to antibodies and in the meantime, dictates the release mechanism of an ADC.